Two oncologists share thoughts about managing expectations while maintaining hope among patients with advanced cancers enrolled in early-stage clinical trials. (ASCO Connection)

Pfizer announced a patent term extension for the breast cancer drug palbociclib (Ibrance), which will extend patent protection by more than 4 years to March 5, 2027.

The PD-L1 inhibitor durvalumab (Imfinzi), with or without the CTLA-4 inhibitor tremelimumab, failed to improve overall survival in recurrent/metastatic, PD-L1-positive head and neck squamous cell carcinoma as compared with cetuximab (Erbitux) and chemotherapy, AstraZeneca announced.

Starting corticosteroids before the CAR T-cell therapy axicabtagene ciloleucel (Yescarta) appeared to reduce the frequency and severity of cytokine release syndrome without affecting efficacy in advanced large B-cell lymphomas, Kite announced.

The contributions of molecular profiling in treatment of gastrointestinal cancers headed a list of advances described in the American Society of Clinical Oncology’s 16th annual Clinical Cancer Advances.

A form of artificial intelligence helped identify patients with lung cancer at risk of hyperprogression when treated with checkpoint inhibitors. (Journal for ImmunoTherapy of Cancer, Case Western Reserve University)

Scientists have combined advances in molecular biology and artificial intelligence to develop a test that may identify liposarcoma quicker and more economically as compared with current tests. (Journal of Molecular Diagnostics)

A decades-long decline in breast cancer mortality among younger women appears to have ended. (Radiological Society of North America)

Herbal cigarettes and related products known as bidis have become widely available online, often marketed as cheaper, safer, and healthier than regular cigarettes. (Tobacco Control)

More evidence that at-home tests for colorectal cancer can increase the percentage of people screened for the disease. (Penn Medicine)

Greater nighttime exposure to outdoor artificial light may increase the risk of thyroid cancer. (Cancer)

Higher circulating levels of melatonin were associated with better survival in men with poor-prognosis prostate cancer. (Oncotarget)

German researchers estimated that as many as 30,000 cancer deaths a year could be prevented if all adults 50 or older in their country took vitamin D supplements. (Molecular Oncology)

  • author['full_name']

    Charles Bankhead is senior editor for oncology and also covers urology, dermatology, and ophthalmology. He joined MedPage Today in 2007. Follow





Source link

Leave a Reply

Your email address will not be published. Required fields are marked *