Studies have revealed an association between vitamin D and conditions such as sepsis​, exacerbation of chronic illnesses, and functional outcomes following falls and fractures​. It has also been linked to a reduction in cardiovascular risk​, inflammation, increased platelet volume, vascular stiffness​ and improved cognitive function​.

Frailty is associated with increased hospital attendance and higher healthcare costs​ and an association has been found between vitamin D deficiency and frailty​.

Prior studies have suggested that vitamin D deficiency is associated with increased risk of hospital re-admission, nursing home admission, and increased hospital LOS​. Whereas some studies have shown an association between vitamin D and conditions leading to admission such as multiple sclerosis and Chronic Obstructive Pulmonary Disease (COPD)​, and infections​.

The aim of the current study was to evaluate the relationship between serum vitamin D and emergency department attendance, hospital admission, and length of stay (LOS) in older Irish community-dwelling adults.

This is the first study to examine the association between vitamin D deficiency and hospitalisation, as opposed to specific diseases or illnesses, in a large population of older adults.

The analysis was conducted in 3093 participants aged 60 years and older recruited to the Trinity-Ulster, Department of Agriculture (TUDA) study through St James’s Hospital, Dublin.

It was a cross-sectional study designed to create a genotype/phenotype database for three population cohorts based on three disease states: cognition, bone health, and hypertension.



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